Google+ Safe Radiotherapy | Archive | Lung Cancer

Lung Cancer

Lung Cancer news and resources

First-line immunotherapy treatment can improve survival for subset of lung cancer patients

First-line immunotherapy treatment can improve survival for subset of lung cancer patients

Findings from a phase III clinical trial for advanced lung cancer patients could help oncologists better predict which patients are likely to receive the most benefit from immunotherapy as a first-line treatment based on the unique molecular characteristics of their tumor, according to a new study reported by a global team led by David Carbone, […]

Discovery could guide immunotherapy for lung cancer

Discovery could guide immunotherapy for lung cancer

Scientists have discovered a new type of immune cell that could predict which lung cancer patients will benefit most from immunotherapy treatment, according to a Cancer Research UK funded study(link is external) published today (Monday) in Nature Immunology. Researchers at the University of Southampton(link is external) and La Jolla Institute for Allergy & Immunology, California(link is […]

Largest genome-wide study of lung cancer susceptibility identifies new causes

Largest genome-wide study of lung cancer susceptibility identifies new causes

A huge study identified several new variants for lung cancer risk that will translate into improved understanding of the mechanisms involved in lung cancer risk. Using the OncoArray genotyping platform developed by multiple cancer consortia, a recent large aggregated genomewide association study identifies new susceptibility loci for lung cancer, the leading cause of cancer mortality […]

Standard dosage for one lung cancer treatment may be too high

Standard dosage for one lung cancer treatment may be too high

A new study published in the Journal of the National Cancer Institute indicates that the customary pembrolizumab dose for treatment of metastatic non-small cell lung cancer may be higher than is needed for effective treatment. In October 2016, pembrolizumab became the new standard of care for firstline treatment of patients with metastatic non-small cell lung […]

T cell revival correlates with lung cancer response to PD-1 immunotherapy

T cell revival correlates with lung cancer response to PD-1 immunotherapy

In lung cancer passives who were attracting immunotherapy narcotizes end the PD-1 pathway, rating for CD8 T cell activation in their blood unreservedly predicted whether their tumors wear wishes a draw back. The denouements are appointed for hebdomadal in PNAS. Benumbs butt PD-1 or its ligand PD-L1 re-activate “fatigued” CD8 T flats by promoting their […]

Fast capture of cancer markers will aid in diagnosis and treatment

Fast capture of cancer markers will aid in diagnosis and treatment

UNIVERSITY PARK, Pa. — A nanoscale product of human cells that was once considered junk is now known to play an important role in intercellular communication and in many disease processes, including cancer metastasis. Researchers at Penn State have developed nanoprobes to rapidly isolate these rare markers, called extracellular vesicles (EVs), for potential development of […]

Gene Editing Technique Helps Find Cancer’s Weak Spots

Gene Editing Technique Helps Find Cancer’s Weak Spots

Genetic mutations that cause cancer also weaken cancer cells, creating an opportunity for researchers to develop drugs that will selectively kill them, while sparing normal cells. This concept is called “synthetic lethality” because the drug is only lethal to mutated (synthetic) cells. Researchers at UC San Diego School of Medicine and Jacobs School of Engineering […]

GARD: A Move Toward Precision Radiation Therapy

GARD: A Move Toward Precision Radiation Therapy

They have developed a clinical genomic-adjusted radiation dose (GARD) model for individualizing radiotherapy based on their previously developed gene-expression radiosensitivity index.1,3 The clinically validated radiosensitivity index score is based on expression of 10 tumor genes: AR, c-Jun, STAT1, PKC–β, RelA, cABL, SUMO1, PAK2, HDAC1, and IRF1.1,3 The radiosensitivity index was validated for patients with breast, […]

Lung Cancer Screening Rates Remain Low

Lung Cancer Screening Rates Remain Low

Very few people who could benefit from lung cancer screening – mostly current and former smokers – are actually getting the tests, according to findings from American Cancer Society researchers. The authors say this means more patients and health care providers need to be informed about the screening guidelines for lung cancer. The study was […]

Murine Study Finds Potential Boost for Ovarian Cancer Drug Olaparib

Murine Study Finds Potential Boost for Ovarian Cancer Drug Olaparib

Newswise — Researchers from the Chinese Academy of Sciences have discovered that the metabolic enzyme phosphoglycerate mutase 1 (PGAM1) helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer drug Olaparib (Lynparza). Their findings in the study “Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in […]

Page 1 of 6123Next ›Last »