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Key to improved cancer immunotherapy

Key to improved cancer immunotherapy

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) have investigated how different subtypes of essential immune-response cells called CD8+ T lymphocytes cooperate to mount a stronger anti-tumor response. The results show that generation of an optimal immune response to cancer requires cooperation between two types of memory T cell — one circulating […]

New way to tackle cancer cells

New way to tackle cancer cells

In-situ assembly of amphiphilic peptides with accompanying cellular functions inside a living cell (i.e., intracellular assembly) and their interaction with cellular components have been emerging as a versatile strategy in controlling cellular fate. However, achieving spatiotemporal control (i.e., inside cellular organelles or other sub-compartments) over the self-assembly of synthetic molecules inside the cell is challenging […]

Better use of current drugs to target cancer

Better use of current drugs to target cancer

A team of researchers at McMaster University has identified a unique feature of cancer stem cells that can be exploited to kill the deadly cells thought to be the reason that cancer comes back after therapy. Understanding this feature will be useful for delivering more targeted cancer therapeutics to the right patients. The study, published […]

First-line immunotherapy treatment can improve survival for subset of lung cancer patients

First-line immunotherapy treatment can improve survival for subset of lung cancer patients

Findings from a phase III clinical trial for advanced lung cancer patients could help oncologists better predict which patients are likely to receive the most benefit from immunotherapy as a first-line treatment based on the unique molecular characteristics of their tumor, according to a new study reported by a global team led by David Carbone, […]

Brain tumors: Still devastating, but treatment has come a long way

Brain tumors: Still devastating, but treatment has come a long way

A brain tumor was the furthest thing from Kathy English’s mind that day in 2003 when she walked into a neurologist’s office. She’d had some uncontrolled sinus issues, so her doctors had ordered a variety of tests, including an MRI. When she arrived to get the MRI results, the neurologist said he had not yet […]

Discovery could guide immunotherapy for lung cancer

Discovery could guide immunotherapy for lung cancer

Scientists have discovered a new type of immune cell that could predict which lung cancer patients will benefit most from immunotherapy treatment, according to a Cancer Research UK funded study(link is external)¬†published today (Monday) in Nature Immunology. Researchers at the University of Southampton(link is external) and La Jolla Institute for Allergy & Immunology, California(link is […]

Cancer Researchers Look at Resistance to Targeted Therapy in Mantle Cell Lymphoma

Cancer Researchers Look at Resistance to Targeted Therapy in Mantle Cell Lymphoma

WASHINGTON (June 14, 2017) — Today some patients suffering with mantle cell lymphoma, a type of blood cancer, can be treated with a pill called Ibrutinib, forgoing conventional chemotherapy. However, many are developing a resistance to this treatment. Research published in Nature Communications by Eduardo Sotomayor, MD, director of the George Washington University Cancer Center […]

Improved accuracy for cancer drug testing

Improved accuracy for cancer drug testing

A method to more accurately test anti-cancer drugs has now been developed at the Sahlgrenska Academy, University of Gothenburg. The method paves the way to a much earlier assessment of who benefits from a specific drug and who does not. “It is common for cancer patients to be prescribed drugs that fail to help them, […]

New Cancer Drug Makes Commonly Prescribed Chemo Drug More Effective When Given Together

New Cancer Drug Makes Commonly Prescribed Chemo Drug More Effective When Given Together

GALVESTON, Texas – Researchers have found a way to increase the effectiveness of a widely used cancer drug while decreasing the risk of heart-damaging side effects, according to a new study by researchers from The University of Texas Medical Branch at Galveston and Texas Tech University Health Sciences Center. The findings are currently available in […]

‘Immunoswitch’ particles may be key to more-effective cancer immunotherapy

‘Immunoswitch’ particles may be key to more-effective cancer immunotherapy

Scientists at Johns Hopkins have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells’ defensive properties while switching on a robust anticancer immune response in mice. Experiments with the tiny, double-duty “immunoswitch” found it able to dramatically slow the growth of mouse melanoma and colon cancer and even eradicate […]

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