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Leukemia

Researchers engineer complex TCR immunotherapy that may target relapsing leukemia

Researchers engineer complex TCR immunotherapy that may target relapsing leukemia

Researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a novel way to genetically engineer T cells that may be effective for treating and preventing leukemia relapse. The findings, published online in the journal Blood, provide the basis for launching a first-in-human clinical trial of this new immunotherapy, which relies on […]

FDA Approves Second Personalized Therapy for Cancer

FDA Approves Second Personalized Therapy for Cancer

A second new personalized treatment for cancer has won approval from the Food and Drug Administration — a clear sign that such treatments will become more widely available for patients with no other options. The treatment is called CAR-T and can have dramatic effects in some patients. But it is both grueling and expensive and […]

Chemo-boosting drug discovered for leukaemia

Chemo-boosting drug discovered for leukaemia

Drugs developed to treat heart and blood vessel problems could be used in combination with chemotherapy to treat an aggressive form of adult leukaemia. Researchers at the Francis Crick Institute, King’s College London and Barts Cancer Institute discovered that acute myeloid leukaemia (AML) – causes bone marrow to ‘leak’ blood, preventing chemotherapy from being delivered properly. Drugs that reversed bone marrow […]

Female cancer survivors are a third less likely to get pregnant

Female cancer survivors are a third less likely to get pregnant

July 3 (UPI) — Research shows that female cancer survivors are one-third less likely to become pregnant compared to women in the general population. A large population study linked all cancers diagnosed in Scotland between 1981 and 2012 to subsequent pregnancies, revealing that women and girls younger than 39 who were cancer survivors were 38 percent […]

Starving prostate cancer with what you eat: Apple peels, red grapes, turmeric

Starving prostate cancer with what you eat: Apple peels, red grapes, turmeric

When you dine on curry and baked apples, enjoy the fact that you are eating something that could play a role starving — or even preventing — cancer. New research from The University of Texas (UT) at Austin, United States (U.S.), identifies several natural compounds found in food, including turmeric, apple peels and red grapes, […]

New driver, target in advanced mucosal melanoma

New driver, target in advanced mucosal melanoma

Not all melanomas are created equal. While most melanomas appear on the skin as the result of sun exposure, a small subset of melanomas arise spontaneously from mucosal tissues. And while targeted treatments and immunotherapies have dramatically improved the prognosis for many patients with sun-associated melanomas, these treatments are ineffective in the mucosal form of […]

A new way to reset gene expression in cancer cells shows promise for leukemia treatment

A new way to reset gene expression in cancer cells shows promise for leukemia treatment

New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia. In recent work published in Nature, they show it’s possible to deactivate cellular programs involved in tumor growth by disrupting a protein that regulates genes. At the center of this research are […]

Yale scientists identify key defect in brain tumor cells

Yale scientists identify key defect in brain tumor cells

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA. They found that the defect is highly sensitive to an existing FDA-approved drug used to treat ovarian cancer — a discovery that challenges current practice for treatment of brain tumors and other cancers […]

Scientists identify molecular therapy to prevent growth of pediatric leukemia

Scientists identify molecular therapy to prevent growth of pediatric leukemia

CHICAGO – Northwestern Medicine scientists have discovered the genetic driver of a rare and lethal childhood leukemia and identified a targeted molecular therapy that halts the proliferation of leukemic cells. The finding also has implications for treating other types of cancer.   Mixed lineage leukemia (MLL) primarily strikes newborns and infants. Less than 10 to 20 […]

New Trial Hopes to Increase Survival for Kids With Cancer, Reduce Risk of Long Term Cardiac Damage

New Trial Hopes to Increase Survival for Kids With Cancer, Reduce Risk of Long Term Cardiac Damage

Newswise — Imagine conquering childhood cancer, only to find out that years down the road your heart may fail. Unfortunately, many children who have battled cancer face this reality. While often lifesaving, the effects of chemotherapy treatment (drugs that kill cancer cells) can take a toll on the developing body of a child, potentially resulting in […]

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