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New way to tackle cancer cells

New way to tackle cancer cells

In-situ assembly of amphiphilic peptides with accompanying cellular functions inside a living cell (i.e., intracellular assembly) and their interaction with cellular components have been emerging as a versatile strategy in controlling cellular fate. However, achieving spatiotemporal control (i.e., inside cellular organelles or other sub-compartments) over the self-assembly of synthetic molecules inside the cell is challenging […]

Cancer Researchers Look at Resistance to Targeted Therapy in Mantle Cell Lymphoma

Cancer Researchers Look at Resistance to Targeted Therapy in Mantle Cell Lymphoma

WASHINGTON (June 14, 2017) — Today some patients suffering with mantle cell lymphoma, a type of blood cancer, can be treated with a pill called Ibrutinib, forgoing conventional chemotherapy. However, many are developing a resistance to this treatment. Research published in Nature Communications by Eduardo Sotomayor, MD, director of the George Washington University Cancer Center […]

New Cancer Drug Makes Commonly Prescribed Chemo Drug More Effective When Given Together

New Cancer Drug Makes Commonly Prescribed Chemo Drug More Effective When Given Together

GALVESTON, Texas – Researchers have found a way to increase the effectiveness of a widely used cancer drug while decreasing the risk of heart-damaging side effects, according to a new study by researchers from The University of Texas Medical Branch at Galveston and Texas Tech University Health Sciences Center. The findings are currently available in […]

New nanotechnology application for difficult-to-treat cancers

New nanotechnology application for difficult-to-treat cancers

A new treatment combining shock waves with nanoparticles can successfully treat tumours that are difficult to target using conventional chemotherapy. This is the first time this combined therapy has been tested in live animals. The findings of this pre-clinical study, published in the journal Endocrine-Related Cancer, could lead to the development of more effective therapies […]

New blood test predicts who will benefit from targeted prostate cancer treatments

New blood test predicts who will benefit from targeted prostate cancer treatments

A new blood test could predict which men with advanced prostate cancer will respond to new targeted treatments for the disease. Researchers were able to detect tumour DNA in men’s blood and pick out cancers with multiple copies of the androgen receptor gene, which many prostate cancers rely on to grow. Men with multiple copies […]

MGH finds current brain cancer treatments cause brain shrinkage

MGH finds current brain cancer treatments cause brain shrinkage

Researchers have found that radiation and chemotherapy may be shrinking patients’ brains, leading researchers to search for new methods to treat brain tumors. Boston Business Journal – The study, to be published in the Aug. 25 issue of the journal Neurology, is the first to examine the effects of radiation and chemotherapy on the healthy […]

Newly identified mechanism of p53-induced cell death could aid cancer therapy

Newly identified mechanism of p53-induced cell death could aid cancer therapy

Research reveals how the tumor suppressor protein p53 works in the cytoplasm to trigger death via apoptosis and identifies a potential cancer therapy strategy. St. Jude Children’s Research Hospital – Researchers have identified a new mechanism that the tumor suppressor protein p53 uses to trigger cell death via apoptosis and have shown how the process […]

FDA Approved Drug Extends Survival for Patients with Rare Cancer

FDA Approved Drug Extends Survival for Patients with Rare Cancer

Sunitinib, an agent approved for use in several cancers, provides unprecedented antitumor activity in thymic carcinoma, a rare but aggressive tumor of the thymus gland, according to a phase II clinical trial led by a researcher at Georgetown Lombardi Comprehensive Cancer Center. The study’s results, published in Lancet Oncology, are the first to demonstrate a […]

Study claims breakthrough in cancer treatment

Study claims breakthrough in cancer treatment

Video Credits to NBCNews.com nbcnews- June 24: In a study released Wednesday, The New England Journal of Medicine is calling a new drug “an entirely new way forward in cancer treatment,” citing stunning results against breast and ovarian cancer associated with a particular gene mutation, and with none of the side effects of traditional chemotherapy. […]

Long-sought drug candidate can halt tumor growth, scientists demonstrate

Long-sought drug candidate can halt tumor growth, scientists demonstrate

Scientists at The Scripps Investigation Institute (TSRI) attempted an equivalent tactic when they attempted to disrupt the function of MYC, a cancer regulator believed to be “undruggable.” The researchers found that a credit card-like molecule they developed somehow moves in and disrupts the important interactions among MYC and its binding partner. MYC is a transcriptional […]

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